Are you by chance using Bandit? I was experiencing a similar symptom, although w/ no resource issues that I noticed, just sudden timeouts that felt like port exhaustion.
If so, there’s a PR @mtrudel put out for thousand_island (Refine acceptor behaviour on abnormal conditions by mtrudel · Pull Request #103 · mtrudel/thousand_island · GitHub) that resolves an issue where the kernel might kill a connection, but the process responsible for it was not restarting since it looked “normal” to it. I was similarly seeing it occur during peaks, but it was mostly just coincidence since that’s when the most activity and aborted connections were occurring. I also saw large numbers of DB timeouts right after, but it was a red herring.
